25+ Years of proven expertise
100+ Chemists dedicated to your success
US & Ireland Facilities for secure, reliable supply

US-Based CDMO for Complex
Small-Molecule and Peptide RSMs

Adesis partners with pharmaceutical companies to develop, optimize, and manufacture regulatory starting materials (RSMs), key starting materials (KSMs), and complex intermediates for drug development programs. Our teams support projects from early route evaluation through process development and non-GMP manufacturing, with capabilities spanning R&D, pilot, and commercial production in the U.S. and Ireland.

Why Companies Choose Adesis for RSM & KSM Supply

  • Strong process chemistry expertise for difficult synthetic routes
  • Domestic manufacturing and secure supply chain support
  • Flexible scale from milligrams to multi-kilogram quantities
  • Fast scientist-to-scientist communication
  • Experience with complex heterocycles and specialty intermediates
  • Support for both early-stage and preclinical development programs

How We Support Your Program

Route Review & Assessment

Evaluation of synthetic feasibility, raw materials, scalability, and timeline.

Process Development & Optimization

Development of robust and scalable chemistry suitable for manufacturing.

Scale-Up & Manufacturing

Production from gram through multi-kilogram quantities in U.S.-based facilities.

Delivery & Ongoing Support

Reliable communication, technical collaboration, and continued supply support as programs advance.

Ready to Accelerate Your Success?

Let’s discuss your technical challenge.