News & Blog

Scaling-up to Manufacturing Level: Adesis has a Team for that

One of the biggest challenges in synthetic chemistry is scaling up small-laboratory syntheses to the manufacturing level … while also producing pure material in a reproducible process.   When a ‘molecule of interest’ is first synthesized in a lab on small scale, a chemist can work tirelessly tweaking reagents, catalysts, solvents, temperatures, concentration, isolation, purification…

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Why I Chose Delaware

By Andrew Cottone, Adesis President When Adesis was just an idea back in the early 2000s, I was a young chemist working in Delaware with a dream of building a premier chemistry solution company with the best chemists in the world. My vision was to partner with biotech and pharma to accelerate their research and…

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Sublimation: Isolating the Purest Chemical Compounds

Sublimation, the conversion of a solid directly into a gas, is a scientific phenomenon that you might not think about often but comes up in your daily life more than you might imagine. Ever use mothballs to keep your clothing protected? Ever order ice cream online from your favorite shop and have it arrive on…

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Expanding Chemical Manufacturing Capacity at Adesis: Meet David Baran

At Adesis, we provide our customers with the highest quality CRO and R&D services to help them solve their complex problems quickly and safely. While that has long involved helping customers develop and perfect reagents and products that they will incorporate into their own manufacturing processes, Adesis is now building the capacity to help customers…

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Flow Chemistry Case Study: The Case of the Low Yielding, Epimerizing Reaction

The Problem: A large pharmaceutical company had a fascinating chemistry problem wherein they were performing a Bestmann Ohira reaction to introduce an alkyne functionality to a crucial, enantiomerically pure intermediate. Beginning with a traditional batch chemistry method, epimerization of the stereo center was observed, resulting in a product with low diastereoselectivity. Seeing all the advantages…

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Adesis Achieves ISO 9001:2015 Certification

New Castle, Delaware – April 20, 2021 – Adesis, Inc., a leading contract research organization and a wholly-owned subsidiary of Universal Display Corporation (Nasdaq:OLED), announced today that it has achieved ISO 9001:2015 certification for its quality management system (QMS). Internationally recognized, this ISO standard is based on a number of quality management principles including a…

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Safety is in Every Element of What We Do

As a contract research organization, the Adesis mission is to solve our clients’ complex chemistry problems and accelerate their research and manufacturing goals. But none of that can be achieved without the certainly that safety standards are met at every phase of the process. That’s because reliably and safely solving the toughest chemistry problems in…

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Meet our VP of Chemistry – John “Jack” Chiarello, PhD.

At Adesis, we take pride in in our deep chemistry expertise that expands with each new challenge our clients bring us. That means collaborating with clients to take compounds from lab to manufacturing – increasing yields, identifying optimal reagents and catalysts, avoiding troublesome isolations and purifications – helping reduce overall costs along the way. Our…

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Of Chemists and Innovation

As a leading chemistry CRO, innovation is our lifeforce. It’s not so surprising when you find out we have a team of 100 chemists — 82 Ph.D. scientists among them — who hold 331 patents, have published 818 peer journal articles and have given more than 398 presentations at scientific symposiums across the globe. You…

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Flow Chemistry: The TARDIS of synthetic chemical techniques

A hallmark of the BBC’s beloved Doctor Who series is the space and time-travelling blue police box known as the TARDIS, which is often described as ‘bigger on the inside.’  What if there were a chemistry technique that shared the same sentiment? Allow me to introduce you to Continuous Flow Chemistry or CFC. It may…

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