Contact our peptide synthesis team for rapid feasibility assessment and transparent project proposals.
Custom peptide synthesis from discovery through commercial scale
Adesis provides comprehensive custom peptide synthesis services for pharmaceutical and biotechnology companies developing next-generation peptide therapeutics. With over 100 chemists –80% PhD-level—and more than 100,000 square feet of US-based facilities, we support projects from milligram quantities through kilogram quantities using integrated solid-phase and solution-phase synthesis approaches.
Our Capabilities
Synthesis Methodologies
- Solid-Phase Peptide Synthesis (SPPS): 0.1-10 mmol scale | Fmoc chemistry | >99% coupling efficiency
- Solution-Phase Synthesis (SPS): Grams to kilograms quantities | Fragment condensation for complex sequences ~20 amino acids
- Peptide-Oligonucleotide Conjugates: Antisense therapeutics & targeted drug delivery
Technical Infrastructure
- CS536X Automated Synthesizer | 20 mL to 2 L vessels | Inert atmosphere | Real-time monitoring
- Purification: SPE | Preparative RP-HPLC | CIEX | Orthogonal strategies for >95% purity
- Analytics: HPLC-MS/UPLC-MS | High-res MS | Multi-nuclei NMR | Amino acid analysis | Peptide mapping
- Quality: ISO 9001:2015 certified | ICH Q7 elements |
Full CoA documentation
Engagement Models
- FTE Model: Dedicated chemist time | Flexible scope | Ideal for early-stage multi-target exploration
- Fee-For-Service: Fixed cost for defined targets | Milestone-based | Best for development & scale-up
