Chromatography: Achieving Product Purity Requirements

In chemistry, chromatography is a process in which a mixture is separated into its various elements for the purposes of either analysis or purification. It’s one of the most common processes we use at Adesis to help our customers develop new molecules, identify unknown chemical entities and achieve their purity requirement.

Different Adesis customers require varying levels of purity in the compounds they’re developing. For pharmaceutical customers, the active pharmaceutical ingredients (APIs) they use in research and development usually require a purity level of between 90 and 95%. Industry manufacturers – for example, a producer of CBD products – might require purity of between 98 and 99%. Whereas manufacturers of organic semiconductors, which perform most efficiently the purer they are, require purity levels above 99%, often up to 99.9%.

Chromatography Presentation on YouTube

As part of our ongoing webinar series Innovation in Small Molecule Purification for Pharmaceutical and Specialty Chemical Industry, Adesis Senior Chemist Wei Bao and Biotage Senior Scientist Bob Bickler recently presented the second webinar in the series: New Age of Chromatography Purification: Strategy for Success. More than 100 viewers joined the webinar during its live presentation and more than 25 have viewed it since.

In the online seminar, Wei and Bob discuss the challenges of chromatography – particularly on a large scale – and how Adesis optimizes the process for our customers by dramatically shortening process runtimes, maximizing purity, reducing the use of raw materials to maximize cost savings on materials and minimize waste, and significantly reduce emissions.

Keep an eye out for our next installment in the series — Speed Up Purification in Manufacturing and Process.